Biochemical Indices of Severity in Human Malaria

Evaluation of C-reactive protein as a biochemical marker for assessing disease severity in Malaria

Levels of C-reactive protein , a well characterised serum acute phase protein were measured in a total of 32 patients admitted to JK hospital with the diagnosis of Malaria (18 vivax malaria and 14 falciparum malaria) . Serum C-reactive protein concentrations were measured daily in all the patients over a seven day period .Percentage parasitemia , platelet count , serum bilirubin , alanine amino...

Biochemical markers of nutritional status and childhood malaria severity in Cameroon.

To investigate the part played by undernutrition in malaria severity, some biomarkers of nutritional status were assessed in children with severe malarial anaemia (MA) and cerebral malaria (CM) in comparison with healthy children or those with uncomplicated malaria. Undernutrition was assessed using the weight-for-age Z score (WAZ). Retinol was determined by HPLC; lipid profile, Ca, Mg and albu...

Severity Assessment with Risk Prediction Using Malaria Severity Score in Patients of Falciparum Malaria

According to the World Malaria Report 2010, there were 225 million cases of malaria and an estimated 781 000 deaths in 2009. Even if the diagnostic features of severe malaria have been set out by W.H.O, there are no objective criteria to quantify the severity of each complication. The aim of the study is to find out the usefulness of malaria severity score to predict to assess severity with ris...

The Impact of IL-18 and IFN-γ on Severity of Malaria and Quality of Treatment

Background & Objective: In human malaria, genotype of cytokines affect immune system. The impact of genotype -137G/C in IL-18 and +874A/T in IFN-γ on the severity of malaria and the quality of treatment – as factors to form asymptomatic persons in endemic regions- has been investigated.Materials & Methods: 100 patients and 102 healthy persons were evaluated by Nested-PCR and thick blood fil...

Transmission Dynamics of Malaria in Human Host: a Neuro-Fuzzy Approach